Quick Verdict: RxSure vs ePrivatePrescription
ePrivatePrescription (ePP) is one of the original UK electronic private prescription platforms. It provides a straightforward system for generating electronic private prescriptions and has strong brand recognition through its exact-match domain. RxSure is a next-generation platform that extends far beyond prescription generation to cover the full patient journey — booking, consultations, prescriptions, payments, and compliance.
Choose ePrivatePrescription if you only need basic electronic prescription generation and prefer an established, single-purpose tool.
Choose RxSure if you want a modern, all-in-one platform that handles booking, SmPC-guided consultations, prescriptions, payments, and compliance management.
What Is ePrivatePrescription?
ePrivatePrescription (ePP) is a UK-based electronic private prescription platform that has been in the market for several years. Its domain — eprivateprescription.com — is an exact keyword match for “electronic private prescription”, giving it strong brand recognition and SEO visibility. The platform provides electronic prescription generation with patient records and prescriber management.
However, ePrivatePrescription focuses primarily on the prescription generation aspect of private prescribing. It does not offer end-to-end patient journey management, integrated payments, SmPC-guided clinical consultations, or multi-site management features.

What Is RxSure?
RxSure is an all-in-one private prescription software platform built for UK pharmacies, clinics, and independent prescribers. It covers the complete private prescribing workflow — from online patient booking and pre-screening through SmPC-guided clinical consultations, electronic prescription generation, integrated payment processing, and GPhC/CQC compliance management.
RxSure charges a flat monthly subscription with no per-prescription fees and zero platform fees on patient payments.
Feature Comparison: RxSure vs ePrivatePrescription
| Feature | RxSure | ePrivatePrescription |
|---|---|---|
| Electronic Prescription Generation | ✓ | ✓ |
| Patient Records Management | ✓ | ✓ |
| Online Patient Booking | ✓ | ✗ |
| SmPC-Guided Consultations | ✓ | ✗ |
| Pre-Screening Questionnaires | ✓ | ✗ |
| Integrated Payment Processing | ✓ | ✗ |
| Multi-Site Management | ✓ | ✗ |
| Staff Training & CPD Tracking | ✓ | ✗ |
| Video Consultations | ✓ | ✗ |
| AI Clinical Support | ✓ | ✗ |
| GPhC + CQC Compliance Dashboard | ✓ | Partial |
| GP Notification Letters | ✓ | ✓ |
Pricing: RxSure vs ePrivatePrescription
RxSure
- Standard: £60/month (free for 3 months)
- Pro: £100/month
- Per-prescription fee: None
- Platform fee on payments: None
- Includes: Booking, consultations, Rx, payments, compliance
ePrivatePrescription
- Pricing model: Subscription-based
- Free trial: Limited
- Includes: Prescription generation, patient records
- Does not include: Booking, consultations, payments
- Additional tools needed: Yes, for full workflow
The value difference is significant: ePrivatePrescription covers prescription generation and basic record-keeping. RxSure’s subscription includes the entire patient journey — booking, SmPC-guided consultations, prescription generation, integrated payments, and compliance management. With RxSure, you replace multiple separate tools with one platform.

Key Differences
1. Prescription Tool vs Complete Platform
ePrivatePrescription is fundamentally a prescription generation tool with patient records. RxSure is an end-to-end platform that manages the complete private prescribing workflow. With ePP, you generate prescriptions. With RxSure, you manage the patient from booking through to payment and follow-up — prescriptions are one step in the journey.
2. Legacy vs Modern Architecture
ePrivatePrescription has been in the market longer and has an established user base. RxSure was built from the ground up with modern technology — responsive design, cloud-based infrastructure, real-time collaboration, and API-first architecture. This matters for speed, reliability, and future feature development.
3. Clinical Safety
RxSure includes SmPC-guided consultation templates with built-in contraindication checks, dosage guidance, and safety warnings. These safety features are embedded directly into the consultation workflow, ensuring every prescription is backed by a documented clinical assessment. ePrivatePrescription handles prescription generation but does not include structured clinical consultation workflows.
4. Scale & Multi-Site
RxSure supports multi-site management for pharmacy groups and clinic chains — centralised compliance, cross-site reporting, per-site branding, and unified patient records. ePrivatePrescription is primarily designed for single-site or individual prescriber use.
Which Should You Choose?
Choose ePrivatePrescription If…
- You only need electronic prescription generation
- You’re an individual prescriber with basic needs
- You already have separate booking and payment systems
- You prefer an established platform with a longer track record
- You don’t need SmPC-guided consultation workflows
Choose RxSure If…
- You want one platform for the complete patient journey
- You value SmPC-guided clinical safety
- You need integrated booking and payment processing
- You manage multiple pharmacy sites or clinic locations
- You need GPhC/CQC compliance management
- You want modern, responsive software with regular updates
Frequently Asked Questions
How does RxSure compare to ePrivatePrescription?
ePrivatePrescription (ePP) is an established prescription generation platform with patient records management. RxSure is a next-generation all-in-one platform that covers the complete patient journey — online booking, SmPC-guided consultations, electronic prescription generation, integrated payment processing, and GPhC/CQC compliance management. While ePP focuses on the prescription step, RxSure manages everything from patient booking to payment.
Is ePrivatePrescription better than RxSure?
ePrivatePrescription has a longer track record and strong brand recognition through its exact-match domain name. However, RxSure offers significantly more features — including online booking, SmPC-guided consultations, integrated payment processing, multi-site management, video consultations, AI clinical support, and comprehensive compliance dashboards. For pharmacies and clinics wanting a complete platform, RxSure provides substantially more value.
Does ePrivatePrescription include consultation workflows?
No. ePrivatePrescription focuses on electronic prescription generation and patient records. It does not include SmPC-guided consultation templates, pre-screening questionnaires, or structured clinical workflows with built-in safety checks. RxSure includes all of these, ensuring every prescription is backed by a documented, compliant clinical assessment with contraindication screening and dosage guidance.
Can I switch from ePrivatePrescription to RxSure?
Yes. RxSure offers a free 3-month trial on the Standard plan, giving you time to set up and test the full platform. Many practices find the transition straightforward since RxSure includes all prescription generation features plus booking, consultations, payments, and compliance tools. The RxSure team provides onboarding support throughout the process.
Does ePrivatePrescription support multi-site pharmacy management?
ePrivatePrescription is primarily designed for single-site or individual prescriber use. It does not offer the multi-site management capabilities needed by pharmacy groups or clinic chains. RxSure includes full multi-site support with centralised compliance dashboards, cross-site reporting, per-site branding, and unified patient records across all locations.
Which platform has better GPhC compliance features?
RxSure. It includes a dedicated GPhC and CQC compliance dashboard with complete audit trails for every consultation, prescription, and patient interaction. SmPC-guided consultation templates ensure every clinical decision is documented. ePrivatePrescription provides basic record-keeping but does not offer pharmacy-specific compliance management tools or inspection-ready audit trail dashboards.
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